curiosityseekerscience

Vaccine development for SARS COV2: - (reverse vaccinology approach.) The approach that we can take to develop vaccine is that we can identify the structure of the surface proteins present on virus and find the genome sequence responsible for the production of these proteins and can engineer the DNA sequence of it by using the recombinant DNA technology. We can copy the DNA sequence to make a huge number of it by the PCR method which will then be utilized to make proteins in another organism from where we would extract the proteins. These proteins will be given along with the adjuvants (i.e. substances that increases the efficacy of vaccine).to the patient so that the patient’s immune system can develop an immune memory which will be utilized whenever a virus attack. Two companies the Sanofi and the GSK have collaborated to develop vaccine against the SARs COV2. 1)       In this collaboration the Sanofi will be contributing the S-protein COVID-19 antig...

Vaccine : - A substance used to stimulate the production of antibodies and provide immunity against one or several diseases, prepared from the causative agent of a disease, its products, or a synthetic substitute, treated to act as an antigen without inducing the disease. Vaccine development strategies in case of viral infection Basically, there are three approaches that we take for vaccine development: - 1)       Traditional Approach 2)       Reverse vaccinology Approach 3)       Structural vaccinology Approach So, we will discuss them one by one: - 1)       Traditional Approach : - This approach generally includes the traditional methods that is the introduction of attenuated or inactivated infectious agent into the body of a person which helps the immune system to have acquired knowledge about the agent/antigen, so that any further introduction of that antigen into the...